Circadian variation in plasma iron concentration and reticuloendothelial iron release in the rat.
نویسندگان
چکیده
1. As in man, the plasma iron concentration in rats exhibits a circadian variation, with an early morning peak and an evening trough. 2. The release into the plasma of iron liberated from haemoglobin within the reticuloendothelial cells of the liver and spleen was studied by injecting heat-damaged erythrocytes containing 59Fe-labelled haemoglobin. 3. The percentage of 59Fe released was lower in the morning than in the evening. 4. These observations suggest that a circadian variation in reticuloendothelial cell behaviour influences the plasma iron concentration.
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ورودعنوان ژورنال:
- Clinical science and molecular medicine
دوره 45 3 شماره
صفحات -
تاریخ انتشار 1973